Download Acute Renal Disorders and Renal Emergencies: Proceedings of by Bernard S. Kaplan M.B., B.Ch., F.C.P.(S.A.), Paul R. Goodyer PDF

By Bernard S. Kaplan M.B., B.Ch., F.C.P.(S.A.), Paul R. Goodyer M.D. (auth.), José Strauss MD (eds.)

My options in regards to the Hemolytic Uremic Syndrome (HUS) received begun in 1961 besides my try to go back to Argentina. As I sought my means in Buenos Aires, I visited Carlos Gianantonio whom I had met in Caracas the yr earlier than in the course of the Pan American pediatric conferences. at the moment he used to be actively engaged on HUS which had turn into a virus in Buenos Aires and different elements of Argentina. i used to be inspired via the staff attempt and devotion of his team to such heavy calls for. They evidently have been assembly the problem at an amazingly excessive point less than a truly crippling actual state of affairs with shortages of area, laboratories and gear. His team including Dr. Becu, on the time the pathologist on the kid's health facility of Buenos Aires (we had met via his mom who used to be instrumental in arranging my go back to Buenos Aires), wrote the various vintage papers on HUS. over the years as Dr. Gianantonio grew to become extra thinking about common pediatrics, the executive elements and its orientation in Latin the US, he grew to become recognized for his deep philosophical questions as to what we're doing and the place we're going. His questions have noticeable implications concerning an agressive method of our pediatric nephrology patients.

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Additional resources for Acute Renal Disorders and Renal Emergencies: Proceedings of Pediatric Nephrology Seminar X held at Bal Harbour, Florida, January 30 – February 3, 1983

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47. : influence of Pattern of platelet serontonin (SRT) , plasma beta-thromboglobulin (BTG) and platelet factor 4 (PF4) in hemolytic uremic syndrome (HUS) in children. Int. J. Pediatr. , 2: 149, 198,. 48. : studies on prosta- glandin metabolism in hemolytic-uremic syndrome. Int. J. Pediatr. , 2: 130, 1981. 49. : in hemolytic uremic syndrome: Impairment of platelet aggregation Evidence for platelet "exhaustion". Blood, 60: 564, 1982. 50. : Elevated B- thromboglobulin in patients with chronic renal failure: hemodialysis.

In a few patients, permanent sequelae were important 45 and sometimes multiple, with school and behavioral problems predominating (Table 3). Table 3. The Central nervous system in HUS. Clinical status of 15 children with sequelae No. of patients Follow up more than 10 years 15 Severe CNS dysfunction (acute stage) 15 Developmental retardation 6 Focal motor deficit 5 Recurrent convulsions 5 Learning problems 7 Language disorders 4 Cortical blindness Behavioral problems 9 Abnormal EEG 13 Abnormal brain CAT scans 12 In many patients the electroencephalograms and the brain CAT scans were abnormal in disproportion to the clinical picture.

15) In that series, serum uric acid levels ranged from normal to as high as 39 mg/dl, and a positive correlation was observed between serum uric acid concentration and BUN on admission. We were unable to derronstrate a correlation between serum uric acid levels and either the BUN or 37 BUN/creatinine ratio in our patients with HOS. HONever, we were able to demonstrate a positive correlation between serum uric acid and serum creatinine concentrations. The absence of a relationship be1:ll7een uric acid am BUN nay be due to the simultaneous influence of the multiple factors leading to hyperuricemia (such as hemolysis) as well as the effects of extrarenal processes on the BUN, including decreases in extracellular volume and increases in tissue catabolism.

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