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By Marc E. de Broe, Patrick C. D’Haese (auth.), Marc E. de Broe, Jack W. Coburn (eds.)

` ... the cloth provided presents priceless details about the organic results and scientific syndromes linked to aluminum publicity. This quantity could be precious for college students and nephrologists who're attracted to furthering their knowing of the area.'
Dialysis and Transplantation, 20/1, January 1991

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Pharmacol Ther 29: 255. 10. Martin RB, 1986: Bioinorganic chemistry of metal ion toxicity. Metal Ions Bioi Syst 20: 21. 11. Martin RB, 1986: The chemistry of aluminum as related to biology and medicine. Clin Chern 32: 1797. 12. Martin RB, 1988: Bioinorganic chemistry of aluminum. Metal Ions Bioi Syst 24: Chapter 1. 13. Martin RB, 1984: Bioinorganic chemistry of calcium. Metal Ions Bioi Syst 17: 1. 14. Margerum DW, Cayley GR, Weatherburn DC, and Pagenkopf GK, 1978: Kinetics and mechanisms of complex formation and ligand exchange.

An energydependent process is suggested by experiments with everted gut sacs from rat small intestine [15]. Parenteral The aluminum contaminating the dialysate [16, 36], and solutions for peritoneal dialysis, hemofiltration or intravenous administration [13, 45], circumvents the natural barriers and may present a hazard even greater than that caused by oral aluminum intake. Due to the strong binding of aluminum to plasma proteins [11], it may be transferred from contaminated dialysate [20] or hemofiltration solutions [45] to plasma against a concentration gradient.

Martin RB, 1988: Bioinorganic chemistry of aluminum. Metal Ions Bioi Syst 24: Chapter 1. 13. Martin RB, 1984: Bioinorganic chemistry of calcium. Metal Ions Bioi Syst 17: 1. 14. Margerum DW, Cayley GR, Weatherburn DC, and Pagenkopf GK, 1978: Kinetics and mechanisms of complex formation and ligand exchange. C. 15. Sternweiss PC and Gilman AG, 1982: Aluminum: A requirement for activation of the regulatory component of adenylate cyclase by fluoride. Proc Nat! Acad Sci 79: 4888. 16. Martin RB, 1983: Hydrolytic equilibria and N7 versus N1 binding in purine nucleosides of cis-diamminedichloroplatinum(II).

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